Researchers from Yale University have discovered a molecular mechanism causing structural abnormalities responsible for lissencephaly, providing a path for potential treatments. Through whole genome sequencing, the research team successfully identified a CRISPR-Cas9 treatment that could both prevent and reverse the effects of the lissencephaly-causing mutations. The team now intends to explore the functions of the mTOR pathway in other genetic forms of lissencephaly.
Alzheimer’s treatment: What’s next beyond amyloid?
In the face of rising global Alzheimer’s rates, a broader range of approaches towards finding a cure is in motion. Apart from the traditional approach
