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Unfolding a Potential Treatment for “Smooth Brain” Disorders

Researchers from Yale University have discovered a molecular mechanism causing structural abnormalities responsible for lissencephaly, providing a path for potential treatments. Through whole genome sequencing, the research team successfully identified a CRISPR-Cas9 treatment that could both prevent and reverse the effects of the lissencephaly-causing mutations. The team now intends to explore the functions of the mTOR pathway in other genetic forms of lissencephaly.

Source: www.genengnews.com –

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