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Study reveals metabolic switch crucial for memory T cell formation and cancer immunity

A metabolic switch is vital for generating memory T cells in the immune system that help with lasting immunity to previous pathogens, according to a Ludwig Cancer Research study. The master regulator of this switch is identified as PPARβ/δ, and this switch’s dysfunction impacts the T cell’s “memory” of previous viruses, in addition to reducing anti-cancer immune responses in mice. Pharmaceutically engaging this switch could enhance cancer immunotherapies’ effectiveness.

Source: www.news-medical.net –

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