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Phage Therapy Could Leverage Retrons to Overcome Antibiotic Resistance

Scientists at the Gladstone Institutes have developed a new methodology for creating genome modifications in phages, utilising bacterial retrons to produce genetic sequences. The retrons, re-engineered to generate recombineering donor DNA, can introduce variants to the phage genome. This may help in finding a solution to antibiotic-resistant bacterial infections, as therapies using these highly-specific viruses are being explored as a potential alternative to antibiotics.

Source: www.genengnews.com –

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