Patients whose breast cancer converted from lymph node-positive to lymph node-negative after neoadjuvant chemotherapy did not have a higher risk of recurrence or death when they skipped adjuvant regional nodal irradiation (RNI), according to a clinical trial. The study’s findings suggest that downstaging cancer-positive regional lymph nodes with neoadjuvant chemotherapy can let some patients skip adjuvant RNI without harming oncologic outcomes.

Sugar-Coated Nanotherapy Halts Alzheimer’s Disease by Trapping Toxic Proteins
Scientists at Northwestern University have developed a method to trap proteins before they form toxic structures that progress neurodegenerative disorders like Alzheimer’s. The approach uses