Scientists from Bristol Myers Squibb and Lund University have outlined how mechanistic modelling can enhance process development for recombinant adeno-associated virus (rAAV)-based therapies. The modelling allows researchers to rapid identify optimal processing conditions and balance purity and yield. It also supports process characterisation needed for commercial process control strategies and is described as a rapid, flexible method for studying challenging parameter spaces.
Y chromosome loss creates hidden cancer vulnerability in men
A study initiated by a University of Arizona Cancer Center physician-scientist Dr. Dan Theodorescu revealed that the loss of the Y chromosome in men’s body
