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Huntington’s Researchers Discover That Protein Aggregates Poke Holes in the Nuclear Membrane

Researchers at Utrecht University have found the aggregates of the toxic protein associated with Huntington’s disease can damage nerve cells by poking holes in the membrane separating the nucleus from the rest of the cell. The team, led by Lukas Kapitein, PhD, also discovered the aggregates could disrupt the protein meshwork fortifying the nuclear envelope, increasing the probability of ruptures.

Source: www.genengnews.com –

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