Researchers have identified extrachromosomal DNA (ecDNA), carrying the MYC oncogene, as a factor contributing to the adaptability of pancreatic cancer. The genetic rings of ecDNA allow tumor cells to quickly increase gene expression, adapt their shape, and survive in harsh environments. The team suggests that detecting or disrupting ecDNA could offer new therapeutic approaches. However, these ideas remain at an early stage.
The True Cost of Focusing on Cost Instead of Cost-Effectiveness
When payors consider only the cost of the medication and not the cost and risk to the patient, doctor, and healthcare system, the irony is
