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Epilepsy drug may alleviate joint degeneration associated with osteoarthritis

A new study in Nature has described Nav1.7 as a key molecule in cartilage cells that can reduce pain and slow progression in osteoarthritis (OA), a widespread joint condition with no effective preventative strategy. The research found that Nav1.7 channels were responsible for over 60% of sodium ion flux within the cells and that the inhibition of their expression improved OA features. The painkiller carbamazepine, approved by the FDA, blocked Nav1.7, suggesting it could be repurposed for OA treatment.

Source: www.news-medical.net –

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