Neurobiologists from Northwestern University have discovered that sleep deprivation reinforces a “tired but wired” mood by increasing dopamine release and synaptic plasticity in the brain. The team’s findings could expand the understanding of mood transition and fast-acting antidepressants, and provide new targets for drugs to treat depression. The researchers induced mild sleep deprivation in mice and found their behavior became more aggressive, hyperactive, and hypersexual compared to those who slept normally.

Trump’s MRI scan raises specter of secrecy in presidential health
President Trump’s off-the-cuff disclosure that he underwent an MRI scan is raising fresh questions about the secrecy surrounding Trump’s health and the need for presidents


