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CD169+ macrophages in lymph node and spleen critically depend on dual RANK and LTbetaR signaling

Significance

The CD169+ macrophages that play an important role in the fight against infections and cancer are receptive to environmental signals for their differentiation. We show that lymph node and splenic CD169+ macrophages require both LTβR and RANK signaling since the conditional…

Source: www.pnas.orgRead more

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