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CAR T-Cell Therapy for Solid Tumors Gets Boost from Cytokine Receptors

Researchers from St Jude’s Children’s Research Hospital have demonstrated that adding a modular chimeric cytokine receptor to chimeric antigen receptor (CAR) T cells increased their efficacy in several solid tumour models. While immunotherapy with modified CAR T cells has previously improved survival rates for paediatric patients with relapsed and recurrent leukaemia, they were less effective at treating solid tumours.

Source: www.genengnews.com –

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