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Macrophages in Newborn, But Not Adult, Mice Help Regenerate Heart Tissue

Newborns’ immune systems are capable of regenerating heart tissue after injury, unlike adults who often suffer from heart failure due to scar tissue. This is because newborn immune system macrophages initiate a process recognized as efferocytosis that enables regeneration of heart muscle. This is not found in adults whose macrophages lead to fibrotic scarring. Scientists suggest that understanding these differences could result in new treatments for adults after heart attacks.

Source: www.genengnews.com –

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